Vizio, “Ovarian metastasis from renal cell carcinoma: a report of three cases

Ovarian metastases from renal cell carcinoma (RCC) are very rare. Over the past 16 years we have encountered 3 examples. The first 2 cases occurred in adults 49 and 50 years old, respectively, who had huge ovarian metastases, clinically detected 12 and 14 months, respectively, after diagnosis of RCC. The third case was a 17-year-old girl in whom a metastatic renal cell carcinoma was detected in an otherwise benign-ap-pearing cystic ovarian mass. To the best of our knowledge only 11 cases of clinically detected ovarian metastases of RCC have been reported. We report 3 new cases and review the literature on the subject. Int J Surg Pathol 11(4):309-312, 2003 Key words: ovarian metastasis, renal cell carcinoma. Although renal cell carcinoma (RCC) may metas-tasize to unusual sites via hematogenous spread [1,2], ovarian metastases are very uncommon [3,4]. The distinction of an ovarian primary tumor from metastatic RCC can be difficult, especially when the ovarian metastasis is discovered first and mimics a primary ovarian clear cell carcinoma. To the best of our knowledge 11 cases of clinically detected ovar-ian metastatic tumor of RCC have been reported in detail [3-7]. We present here the clinicopathologic findings of 3 new cases found in the files of our De-partment from 1985 to 2000